Basic Science RCR

Registration for Basic Science Responsible Conduct of Research Course - Winter 2024 is now closed.

The Basic Science Responsible Conduct of Research Course is changing. The course will be offered beginning February 9, 2024, through April 5, 2024. Registration is now closed.

All lectures for the winter 2024 course will be delivered in person by Tori Sharma, UC Berkeley RCR Program Manager and include invited lecturers from UCSF CARE Team, UCSF OCPD, and the UCSF Compliance and COI Team.

In-person course lecture dates and times are Fridays, 1:00 p.m. - 2:15 p.m. Sessions split between Parnassus and Mission Bay campuses.

Over the course of the series, learners will attend 8 lectures in person. See the full syllabus. If you are a Postdoc approved to work in a fully remote environment, please consult your Program Director for guidance.

Discussion groups will be delivered by UCSF faculty facilitators via Zoom on Mondays following the lectures from 1:00 p.m.–2:30 p.m.

The information on this page is for UCSF researchers engaged in basic science research seeking to meet the NIH requirements for training in responsible conduct in research. If your research work is with human subjects or data derived from human subjects, please go to the Human Subjects RCR page.

The UCSF Basic Science Responsible Conduct of Research Program is a course designed to satisfy NIH and NSF requirements for training in the responsible conduct of research for postdoctoral scholars and faculty at all career levels . The Basic Science RCR Course utilizes a combination of 75 minute in-person lectures, case studies and virtual faculty-facilitated 90 minute discussions.

Basic Science Responsible Conduct of Research Course

Course Description

The purpose of this course is to ensure that basic science researchers are well versed with respect to training in responsible conduct in research (RCR). Attendees also gain an understanding of federal, state, and UCSF policies and resources available to further support their research endeavors.

Methods of Instruction:

Course meetings include lectures, case studies, and group discussions.
Discussion section meetings include case studies and interactive group discussions in smaller groups.

Discussion Topics Schedule

Session 1: The Reproducibility Crisis

Types of Scientific Research at UCSF
Views about Scientists as Responsible Members of Society
Best Practices in Rigor and Reproducibility - workshop
Anonymous survey on misconduct and reproducibility
Best Practices in Mentorship - workshop

Session 2: Research Misconduct and Social Responsibility

New Guidance on Foreign Influence and Research Security
Conflicts of Interest Overview & Importance of Addressing Conflicts
Contemporary Ethical issues in Biomedical Research
Social and Environmental Impacts of Research

Session 3: Responsible Authorship, Publication, and Peer Review

Best Practices in Data Management - Qualitative and Quantitative
New Federal Sharing Requirements
Developing a Data Management Plan (DMP)
Open AI, Generative AI, Data Manipulation and Plagiarism
Data transparency information from Nature and Cell Press journals (refer to comprehensive checklists)
Statistical Analysis of Biological Data (See UCSF Library Resources)
Data Sharing during PI Transitions

Session 4: Mentor/Mentee Responsibilities and Relationships

Human Subjects Research -- COVID-19 Vaccines and CRISPR Therapies
Informed Consent Monitoring
Protection of Laboratory Animals and the Role of Postdocs in Animal Welfare
Approved Lab Researchers and IACUC Protocols
Policies and Best Practices on Laboratory Safety, Biosafety, and Animal Research Subjects

Session 5: The Protection of Human Subjects and Welfare of Laboratory Animals

Best Practices in Authorship and Publication - workshop
Ethics and Ownership of Discoveries
New Guidance on Text Recycling
Practicing Responsible Peer review and Becoming a Reviewer

Session 6: Conflicts of Interest and Collaborative Research and Professionalism

Developing Inclusive Research Communities (Racism in Science)
Prevention of Sexual Harassment and Violence
Appropriate Support and Management of Postdocs with Disabilities
Bullying, Civility, Harassment, and Inappropriate Behavior in Research Environments
Effective Collaboration in Research

Session 7: Ethical Behavior in Mentoring Research Trainees

Appropriate Mentoring and Lab Relationships between PIs and Postdocs
Strategies for Having Difficult Conversations
Resolving Conflicts and Communicating with Impact
Mentor/Mentee Responsibilities and Relationships
Mentoring Frameworks and Self Advocacy

Session 8: UCSF Postdoc Trainee Ethics and Compliance Conflicts of Interest

Understand UCSF COI requirements for Postdocs UPAY585 - personal, professional, financial
Postdoc Outside Professional Activity at UCSF
Building a Career-Long Positive Attitude toward Research Ethics
Reporting UCSF Conflicts of Interest

Offered to UCSF researchers who conduct basic (non-human subjects) research, Basic Science RCR is an eight-session course designed to satisfy NIH and NSF requirements for training in the responsible conduct of research. The course utilizes a combination of faculty presentations and in-person case study discussions to address contemporary debates at the interface between biomedical science and society.

Basic Science RCR is offered once a year during the winter quarter, meeting weekly for eight weeks. Registration for the course opens in the preceding November/December.

In addition to in-person lectures and discussion groups, learners will also be given access to additional resources and are able participate in an online ethics forum. The online ethics forum provides a way for learners to continue class discussions; ask questions of course faculty and peers; post relevant articles, resources, and case studies; share their own experiences; and voice their concerns and opinions. The website is password-protected, and all comments remain confidential.

The course website also serves as a centralized repository of Basic Science RCR resources and information and is a site where postdocs from different campus locations can form a community and maintain contact.

Attendance at all sessions is required to receive a certificate or course completion letter.

NIH Requirements

In general, NIH requires RCR training every four years and at each stage of training (graduate, postdoc, early faculty, etc). Basic Science RCR is a necessary, but not always sufficient, component of training in responsible conduct of research. Please be sure to contact your funding agency to inquire about additional requirements beyond those provided in Basic Science RCR.

Is Basic Science RCR for me? Am I eligible and required to take the course?

Am I eligible to take Basic Science RCR? This class is open to all UCSF faculty and postdoctoral trainees who’s research is primarily wet lab based or computational using non-human subjects derived data. 5^th year graduate students who need to take an RCR refresher course are also eligible, but should enroll in the RCR course that best fits their research agenda. If you have questions about your eligibility, please email the program coordinator at [email protected].

Am I required to take Basic Science RCR? The NIH, NSF, and other federal funders require all funded trainees to take Responsible Conduct of Research at least every four years and at least once per career level. This applies to all levels of training grants (e.g. T32 for postdoctoral scholars or K awards for faculty).

Postdoctoral scholars are strongly advised to take RCR in their first year of training, even if you received training recently as a graduate student.

If you are not sure if you are required to take RCR, please contact us or your program administrator. Faculty and postdoctoral scholars not funded by NIH or NSF are still strongly encouraged to enroll.

For Postdocs Applying to an NIH Fellowship (e.g., F or K awards)

A plan for instruction in RCR is required of all Fellowship applicants. The Basic Science RCR or Human Subjects RCR course is a key component of this requirement and may be supplemented by lectures, panel discussions, or colloquia providing refreshers on topics of specific ethical concern in the trainees’ field not covered by UCSF RCR courses. See the Training Program Faculty & Admin page for sample grant text on UCSF RCR offerings.